Long term follow up of chronic hepatitis B virus infection in intravenous drug abusers and homosexual men.

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Long term follow up of chronic hepatitis B virus infection in intravenous drug abusers and homosexual men.

Long term follow up of 16 homosexual men and 78 intravenous drug abusers who were chronic carriers of hepatitis B surface antigen (HBsAg) showed fundamental differences between the two groups. Viral replication, expressed by the presence of hepatitis B e antigen, lasted for four years or more in 10 out of 14 (71%) of the homosexual men whereas it was not present in 43 out of 73 (59%) of the dru...

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Serological and histological follow up of chronic hepatitis B infection.

In order to study the clinical, serological, and morphological evolution of chronic hepatitis B virus infection in childhood, a prospective study has been carried out. A total of 90 children with a chronic infection were followed up for a mean (SD) of 3 (1.8) years. At the beginning of the study, 61 children were asymptomatic and 77 were household contacts of chronic carriers. Serologically 77 ...

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Evaluation of miR-101 Level in Patients with Chronic Hepatitis B Virus Infection and Liver Cirrhosis

ABSTRACT        Background and Objective: MiRNAs are small RNAs that are expressed in most eukaryotes, and can regulate gene expression by attaching to the 3’ end of target mRNA. MicroRNA-101 (miR-101) post-transcriptional regulation is important for host-virus interactions. In addition, miR-101 has a tumor suppressive role in liver cancer and metastasis, an...

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Chronic active hepatitis in intravenous drug abusers may be delta agent infection associated.

Since the delta agent was first identified by Rizzetto and his colleagues in 1977 there has been much speculation regarding its nature and significance. The delta agent appears to be an RNA virus which is dependent on hepatitis B surface antigen (HBsAg) for its replication (Rizzetto et al, 1980). Chronic HBsAg carriers appear to be most at risk of developing delta infection (Smedile et al, 1981...

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Osteoarticular infection in intravenous drug abusers: influence of HIV infection and differences with non drug abusers.

OBJECTIVES To determine (a) the influence of HIV in developing osteoarticular infections in intravenous drug abusers (IVDAs) and (b) the differences between the clinical features of osteoarticular infections in IVDAs and a control group of non-IVDAs. METHODS A comparative study of the clinical features of osteoarticular infections in all HIV positive and HIV negative IVDAs admitted to the dep...

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ژورنال

عنوان ژورنال: BMJ

سال: 1986

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.292.6524.854